小鼠 Brdt (NM_001079873) cDNA克隆

Accession: NM_001079873
基因名称: Brdt
基因别名: Brd6; Fsrg3; 7420412D09Rik
基因描述: Mus musculus bromodomain, testis-specific (Brdt), transcript variant 2, mRNA.
种属: Mouse
CDS区长度: 981 (查看编码区序列)
翻译后氨基酸长度: 326 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, compared to variant 1, resulting in a shorter protein (isoform B) that lacks the 3' bromodomain and ET domain, compared to isoform A.
产品编号 产品名称 载体 规格 价格
G128146 小鼠 Brdt (NM_001079873) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the BET protein family. BET proteins have two N-terminal bromodomains and one C-terminal extraterminal domain (ET domain). BET proteins regulate chromatin reorganization via binding to acetylated histones. This gene is thought to play a role in the transcriptional regulation of spermatogenesis. Although referred to as testis-specific bromodomain (Brdt) protein, RT-PCR indicates that this gene is expressed in both mouse oocytes and testes. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Jul 2008]