小鼠 Acox1 (NM_015729) cDNA克隆

Accession: NM_015729
基因名称: Acox1
基因别名: AOX; Acox; Paox; D130055E20Rik
基因描述: Mus musculus acyl-Coenzyme A oxidase 1, palmitoyl (Acox1), transcript variant 1, mRNA.
种属: Mouse
CDS区长度: 1986 (查看编码区序列)
翻译后氨基酸长度: 661 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes isoform 1.
产品编号 产品名称 载体 规格 价格
G128060 小鼠 Acox1 (NM_015729) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the acyl-coenzyme A oxidase family. The encoded protein is localized to peroxisomes and is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-coenzyme A to 2-trans-enoyl-coenzyme A. Disruption of this gene results in microvesicular steatohepatitis, spontaneous peroxisome proliferation, and the eventual development of hepatocellular carcinomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]