人 ME3 (NM_001161586) cDNA克隆

Accession: NM_001161586
基因名称: ME3
基因别名: NADP-ME
基因描述: Homo sapiens malic enzyme 3, NADP(+)-dependent, mitochondrial (ME3), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1815 (查看编码区序列)
翻译后氨基酸长度: 604 (查看氨基酸序列)
Transcript Variant: This variant (3) has an alternate 5' UTR and encodes the same protein, as compared to variant 1.
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G127404 人 ME3 (NM_001161586) cDNA克隆 pDONR223 2ug质粒 点击询价

Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]