IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.[supplied by OMIM, Mar 2008]
Accession: | NM_006663 |
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基因名称: | PPP1R13L |
基因别名: | RAI; RAI4; IASPP; NKIP1 |
基因描述: | Homo sapiens protein phosphatase 1, regulatory subunit 13 like (PPP1R13L), transcript variant 2, mRNA. |
种属: | Human |
CDS区长度: | 2487 (查看编码区序列) |
翻译后氨基酸长度: | 828 (查看氨基酸序列) |
Transcript Variant: | This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. |
人 PPP1R13L (NM_001142502) cDNA克隆 | transcript variant 1 |
人 PPP1R13L (NM_006663) cDNA克隆 | transcript variant 2 |
IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.[supplied by OMIM, Mar 2008]