人 PDE10A (NM_001130690) cDNA克隆

Accession: NM_001130690
基因名称: PDE10A
基因别名: HSPDE10A
基因描述: Homo sapiens phosphodiesterase 10A (PDE10A), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2370 (查看编码区序列)
翻译后氨基酸长度: 789 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the protein-coding transcript.
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G127364 人 PDE10A (NM_001130690) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011]