人 VAV3 (NM_001079874) cDNA克隆

基本信息

Accession: NM_001079874
基因名称: VAV3
基因描述: Homo sapiens vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 864 (查看编码区序列)
翻译后氨基酸长度: 287 (查看氨基酸序列)
Transcript Variant: This variant (2, also known as vav3.1) contains a novel 5' exon, and is missing most of the exons found in the 5' half of variant 1. This is a shorter isoform, and consists mostly of the C-terminal SH3-SH2-SH3 region.

订购信息

产品编号 产品名称 载体 规格 价格
G126832 人 VAV3 (NM_001079874) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 VAV3 (NM_006113) cDNA克隆 transcript variant 1
人 VAV3 (NM_001079874) cDNA克隆 transcript variant 2

基因简介

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

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