人 TMED7-TICAM2 (NM_001164469) cDNA克隆

基本信息

Accession: NM_001164469
基因名称: TMED7-TICAM2
基因别名: TAG
基因描述: Homo sapiens TMED7-TICAM2 readthrough (TMED7-TICAM2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 567 (查看编码区序列)
翻译后氨基酸长度: 188 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate splice site that causes an early stop codon in the 3' coding region, compared to variant 1. The encoded isoform (2) has a shorter C-terminus and shares no sequence identity with the downstream TICAM2 gene product, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G126205 人 TMED7-TICAM2 (NM_001164469) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TMED7-TICAM2 (NM_001164468) cDNA克隆 transcript variant 1
人 TMED7-TICAM2 (NM_001164469) cDNA克隆 transcript variant 2

基因简介

This locus represents naturally occurring read-through transcription between the neighboring transmembrane emp24 protein transport domain containing 7 (TMED7) and toll-like receptor adaptor molecule 2 (TICAM2) genes. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with the products of each individual gene. This fusion product functions to negatively regulate the adaptor MyD88-independent toll-like receptor 4 pathway. [provided by RefSeq, Nov 2010]

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