The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011]
人 PDE7A (NM_001242318) cDNA克隆
| Accession: | NM_001242318 |
|---|---|
| 基因名称: | PDE7A |
| 基因别名: | HCP1; PDE7 |
| 基因描述: | Homo sapiens phosphodiesterase 7A (PDE7A), transcript variant 3, mRNA. |
| 种属: | Human |
| CDS区长度: | 1449 (查看编码区序列) |
| 翻译后氨基酸长度: | 482 (查看氨基酸序列) |
| Transcript Variant: | This variant (3, also called PDE7A1) represents the longer transcript, and encodes the longer isoform (c). |
| 人 PDE7A (NM_002603) cDNA克隆 | transcript variant 1 |
| 人 PDE7A (NM_001242318) cDNA克隆 | transcript variant 3 |
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