This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis.[provided by RefSeq, Oct 2010]
人 IRGM (NM_001145805) cDNA克隆
| Accession: | NM_001145805 |
|---|---|
| 基因名称: | IRGM |
| 基因别名: | IFI1; IRGM1; LRG47; LRG-47 |
| 基因描述: | Homo sapiens immunity-related GTPase family, M (IRGM), mRNA. |
| 种属: | Human |
| CDS区长度: | 546 (查看编码区序列) |
| 翻译后氨基酸长度: | 181 (查看氨基酸序列) |
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