人 DCK (NM_000788) cDNA克隆

Accession: NM_000788
基因名称: DCK
基因描述: Homo sapiens deoxycytidine kinase (DCK), mRNA.
种属: Human
CDS区长度: 783 (查看编码区序列)
翻译后氨基酸长度: 260 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G125291 人 DCK (NM_000788) cDNA克隆 pDONR223 2ug质粒 点击询价

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008]