人 GRIN2A (NM_001134408) cDNA克隆

基本信息

Accession: NM_001134408
基因名称: GRIN2A
基因别名: LKS; EPND; FESD; NR2A; GluN2A; NMDAR2A
基因描述: Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 2A (GRIN2A), transcript variant 3, mRNA.
种属: Human
CDS区长度: 3846 (查看编码区序列)
翻译后氨基酸长度: 1281 (查看氨基酸序列)
Transcript Variant: This variant (3) is alternatively spliced at the 3' end compared to variant 1, resulting in a frame-shift and a shorter isoform (2) with a different C-terminus compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G124824 人 GRIN2A (NM_001134408) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 GRIN2A (NM_001134407) cDNA克隆 transcript variant 1
人 GRIN2A (NM_000833) cDNA克隆 transcript variant 2
人 GRIN2A (NM_001134408) cDNA克隆 transcript variant 3

基因简介

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

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