人 ERBB2IP (NM_018695) cDNA克隆

基本信息

Accession: NM_018695
基因名称: ERBB2IP
基因别名: LAP2; ERBIN
基因描述: Homo sapiens erbb2 interacting protein (ERBB2IP), transcript variant 2, mRNA.
种属: Human
CDS区长度: 4116 (查看编码区序列)
翻译后氨基酸长度: 1371 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an exon in the 3' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G124809 人 ERBB2IP (NM_018695) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ERBB2IP (NM_001253697) cDNA克隆 transcript variant 1
人 ERBB2IP (NM_018695) cDNA克隆 transcript variant 2
人 ERBB2IP (NM_001253698) cDNA克隆 transcript variant 4
人 ERBB2IP (NM_001006600) cDNA克隆 transcript variant 7
人 ERBB2IP (NM_001253699) cDNA克隆 transcript variant 8
人 ERBB2IP (NM_001253701) cDNA克隆 transcript variant 9

基因简介

This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

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