人 PDE11A (NM_001077358) cDNA克隆

基本信息

Accession: NM_001077358
基因名称: PDE11A
基因别名: PPNAD2
基因描述: Homo sapiens phosphodiesterase 11A (PDE11A), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1728 (查看编码区序列)
翻译后氨基酸长度: 575 (查看氨基酸序列)
Transcript Variant: This variant (2) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 4. The resulting isoform (2) has a shorter N-terminus, compared to isoform 4.

订购信息

产品编号 产品名称 载体 规格 价格
G124730 人 PDE11A (NM_001077358) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PDE11A (NM_001077196) cDNA克隆 transcript variant 1
人 PDE11A (NM_001077358) cDNA克隆 transcript variant 2
人 PDE11A (NM_001077197) cDNA克隆 transcript variant 3
人 PDE11A (NM_016953) cDNA克隆 transcript variant 4

基因简介

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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