人 OSBP2 (NM_001282741) cDNA克隆

Accession: NM_001282741
基因名称: OSBP2
基因别名: HLM; ORP4; ORP-4; OSBPL1; OSBPL4
基因描述: Homo sapiens oxysterol binding protein 2 (OSBP2), transcript variant 6, mRNA.
种属: Human
CDS区长度: 1980 (查看编码区序列)
翻译后氨基酸长度: 659 (查看氨基酸序列)
Transcript Variant: This variant (6) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses an alternate in-frame splice site, compared to variant 1. It represents use of an internal promoter and initiates translation at an alternate start codon. The encoded isoform (f) is shorter and has a distinct N-terminus, compared to isoform a.
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G124584 人 OSBP2 (NM_001282741) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2013]