人 PTPRR (NM_130846) cDNA克隆

基本信息

Accession: NM_130846
基因名称: PTPRR
基因别名: PTPRQ; EC-PTP; PCPTP1; PTP-SL; PTPBR7
基因描述: Homo sapiens protein tyrosine phosphatase, receptor type, R (PTPRR), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1239 (查看编码区序列)
翻译后氨基酸长度: 412 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2, also referred to as isoform gamma) has a distinct N-terminus and is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G124329 人 PTPRR (NM_130846) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PTPRR (NM_002849) cDNA克隆 transcript variant 1
人 PTPRR (NM_130846) cDNA克隆 transcript variant 2
人 PTPRR (NM_001207015) cDNA克隆 transcript variant 3
人 PTPRR (NM_001207016) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]

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