人 RSPO1 (NM_001242909) cDNA克隆

Accession: NM_001242909
基因名称: RSPO1
基因别名: RSPO; CRISTIN3; RP11-566C13.1
基因描述: Homo sapiens R-spondin 1 (RSPO1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 711 (查看编码区序列)
翻译后氨基酸长度: 236 (查看氨基酸序列)
Transcript Variant: This variant (3) reflects use of an alternate splice donor site, compared to variant 1. Translation is predicted to initiate at an alternate ATG site resulting in a protein (isoform 2) with a short novel N-terminus compared to isoform 1.
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G123952 人 RSPO1 (NM_001242909) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. [provided by RefSeq, Jul 2008]