人 RNF14 (NM_183399) cDNA克隆

基本信息

Accession: NM_183399
基因名称: RNF14
基因别名: ARA54; HFB30; TRIAD2; HRIHFB2038
基因描述: Homo sapiens ring finger protein 14 (RNF14), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1425 (查看编码区序列)
翻译后氨基酸长度: 474 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Both variants encode the same isoform (1).

订购信息

产品编号 产品名称 载体 规格 价格
G123592 人 RNF14 (NM_183399) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RNF14 (NM_004290) cDNA克隆 transcript variant 1
人 RNF14 (NM_183398) cDNA克隆 transcript variant 2
人 RNF14 (NM_183399) cDNA克隆 transcript variant 3
人 RNF14 (NM_183400) cDNA克隆 transcript variant 4
人 RNF14 (NM_183401) cDNA克隆 transcript variant 5
人 RNF14 (NM_001201365) cDNA克隆 transcript variant 6

基因简介

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011]

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