The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion. [provided by RefSeq, Jul 2008]
人 GABRB2 (NM_000813) cDNA克隆
| Accession: | NM_000813 |
|---|---|
| 基因名称: | GABRB2 |
| 基因描述: | Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 2 (GABRB2), transcript variant 2, mRNA. |
| 种属: | Human |
| CDS区长度: | 1425 (查看编码区序列) |
| 翻译后氨基酸长度: | 474 (查看氨基酸序列) |
| Transcript Variant: | This variant (2) lacks 114 bp within the coding region, as compared to variant 1, resulting in an isoform (2) which is 38 aa shorter. |
| 人 GABRB2 (NM_021911) cDNA克隆 | transcript variant 1 |
| 人 GABRB2 (NM_000813) cDNA克隆 | transcript variant 2 |
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