人 PDE4C (NM_001098819) cDNA克隆

Accession: NM_001098819
基因名称: PDE4C
基因别名: DPDE1
基因描述: Homo sapiens phosphodiesterase 4C, cAMP-specific (PDE4C), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1821 (查看编码区序列)
翻译后氨基酸长度: 606 (查看氨基酸序列)
Transcript Variant: This variant (2) contains an alternate 5' terminal exon compared to variant 1. This results in translation initiation from an in-frame downstream AUG, and an isoform (PDE4C2) with a shorter N-terminus compared to isoform PDE4C1.
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G123361 人 PDE4C (NM_001098819) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]