人 THEMIS (NM_001164687) cDNA克隆

Accession: NM_001164687
基因名称: THEMIS
基因别名: GASP; SPOT; TSEPA; C6orf190; C6orf207; bA325O24.3; bA325O24.4
基因描述: Homo sapiens thymocyte selection associated (THEMIS), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1821 (查看编码区序列)
翻译后氨基酸长度: 606 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, uses a downstream translational start codon, and lacks an alternate in-frame exon in the central coding region, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
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G122949 人 THEMIS (NM_001164687) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]