人 PTPRD (NM_130392) cDNA克隆

基本信息

Accession: NM_130392
基因名称: PTPRD
基因别名: HPTP; PTPD; HPTPD; HPTPDELTA; RPTPDELTA
基因描述: Homo sapiens protein tyrosine phosphatase, receptor type, D (PTPRD), transcript variant 3, mRNA.
种属: Human
CDS区长度: 4521 (查看编码区序列)
翻译后氨基酸长度: 1506 (查看氨基酸序列)
Transcript Variant: This variant (3) has multiple differences in the coding region, compared to variant 1, resulting in an isoform (3) that is shorter than isoform 1. The 5' UTR of this variant is incomplete because no 5' complete transcripts representing this variant exist, and there are alternate splicing choices in the upstream region.

订购信息

产品编号 产品名称 载体 规格 价格
G122663 人 PTPRD (NM_130392) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PTPRD (NM_002839) cDNA克隆 transcript variant 1
人 PTPRD (NM_130391) cDNA克隆 transcript variant 2
人 PTPRD (NM_130392) cDNA克隆 transcript variant 3
人 PTPRD (NM_130393) cDNA克隆 transcript variant 4
人 PTPRD (NM_001040712) cDNA克隆 transcript variant 5
人 PTPRD (NM_001171025) cDNA克隆 transcript variant 6

基因简介

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jan 2010]

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