人 EFNA4 (NM_182690) cDNA克隆

基本信息

Accession: NM_182690
基因名称: EFNA4
基因别名: EFL4; EPLG4; LERK4
基因描述: Homo sapiens ephrin-A4 (EFNA4), transcript variant 3, mRNA.
种属: Human
CDS区长度: 582 (查看编码区序列)
翻译后氨基酸长度: 193 (查看氨基酸序列)
Transcript Variant: This variant (3), also known as ephrin-A4 (s), uses an alternate splice site in the 3' coding region, compared to variant 1, that results in a downstream translation termination. It encodes isoform c which has a distinct and slightly shorter C-terminus compared to isoform a. Isoform c lacks a characteristic transmembrane domain and the GPI-signal sequence contained in isoform a. Isoform c is a secreted molecule.

订购信息

产品编号 产品名称 载体 规格 价格
G121816 人 EFNA4 (NM_182690) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 EFNA4 (NM_005227) cDNA克隆 transcript variant 1
人 EFNA4 (NM_182689) cDNA克隆 transcript variant 2
人 EFNA4 (NM_182690) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin. Three transcript variants that encode distinct proteins have been identified. [provided by RefSeq, Jul 2008]

相关产品