人 EDNRB (NM_003991) cDNA克隆

基本信息

Accession: NM_003991
基因名称: EDNRB
基因别名: ETB; ET-B; ETBR; ETRB; HSCR; WS4A; ABCDS; ET-BR; HSCR2
基因描述: Homo sapiens endothelin receptor type B (EDNRB), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1311 (查看编码区序列)
翻译后氨基酸长度: 436 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR, 3' UTR, and 3' coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G121704 人 EDNRB (NM_003991) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 EDNRB (NM_000115) cDNA克隆 transcript variant 1
人 EDNRB (NM_003991) cDNA克隆 transcript variant 2
人 EDNRB (NM_001122659) cDNA克隆 transcript variant 3
人 EDNRB (NM_001201397) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

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