人 UBASH3A (NM_001243467) cDNA克隆

Accession: NM_001243467
基因名称: UBASH3A
基因别名: TULA; CLIP4; STS-2; TULA-1
基因描述: Homo sapiens ubiquitin associated and SH3 domain containing A (UBASH3A), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1581 (查看编码区序列)
翻译后氨基酸长度: 526 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region, and two alternate exons that result in a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (3) has a distinct C-terminus and is shorter than isoform 1.
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G121049 人 UBASH3A (NM_001243467) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes one of two family members belonging to the T-cell ubiquitin ligand (TULA) family. Both family members can negatively regulate T-cell signaling. This family member can facilitate growth factor withdrawal-induced apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]