人 HCST (NM_001007469) cDNA克隆

Accession: NM_001007469
基因名称: HCST
基因别名: DAP10; KAP10; PIK3AP
基因描述: Homo sapiens hematopoietic cell signal transducer (HCST), transcript variant 2, mRNA.
种属: Human
CDS区长度: 279 (查看编码区序列)
翻译后氨基酸长度: 92 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in a shorter protein (isoform 2).
产品编号 产品名称 载体 规格 价格
G120798 人 HCST (NM_001007469) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]