人 BCOR (NM_017745) cDNA克隆

Accession: NM_017745
基因名称: BCOR
基因别名: MAA2; ANOP2; MCOPS2
基因描述: Homo sapiens BCL6 corepressor (BCOR), transcript variant 1, mRNA.
种属: Human
CDS区长度: 5166 (查看编码区序列)
翻译后氨基酸长度: 1721 (查看氨基酸序列)
Transcript Variant: This variant (1) uses an alternate in-frame splice site compared to variant 5. The resulting isoform (a) has the same N- and C-termini but is shorter compared to isoform c. Variants 1 and 3 both encode the same isoform (a).
产品编号 产品名称 载体 规格 价格
G120762 人 BCOR (NM_017745) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.[provided by RefSeq, Jun 2010]