人 TRMU (NM_001282785) cDNA克隆

基本信息

Accession: NM_001282785
基因名称: TRMU
基因别名: MTO2; MTU1; TRMT; TRMT1; TRNT1
基因描述: Homo sapiens tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase (TRMU), transcript variant 7, mRNA.
种属: Human
CDS区长度: 1131 (查看编码区序列)
翻译后氨基酸长度: 376 (查看氨基酸序列)
Transcript Variant: This variant (7) lacks an alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (g) is shorter and has a distinct C-terminus, compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G120745 人 TRMU (NM_001282785) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TRMU (NM_018006) cDNA克隆 transcript variant 1
人 TRMU (NM_001282782) cDNA克隆 transcript variant 3
人 TRMU (NM_001282783) cDNA克隆 transcript variant 5
人 TRMU (NM_001282784) cDNA克隆 transcript variant 6
人 TRMU (NM_001282785) cDNA克隆 transcript variant 7

基因简介

This nuclear gene encodes a mitochondrial tRNA-modifying enzyme. The encoded protein catalyzes the 2-thiolation of uridine on the wobble positions of tRNA(Lys), tRNA(Glu), and tRNA(Gln), resulting in the formation of 5-taurinomethyl-2-thiouridine moieties. Mutations in this gene may cause transient infantile liver failure. Polymorphisms in this gene may also influence the severity of deafness caused by mitochondrial 12S ribosomal RNA mutations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

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