人 GSR (NM_001195104) cDNA克隆

基本信息

Accession: NM_001195104
基因名称: GSR
基因描述: Homo sapiens glutathione reductase (GSR), transcript variant 4, mRNA.
种属: Human
CDS区长度: 1323 (查看编码区序列)
翻译后氨基酸长度: 440 (查看氨基酸序列)
Transcript Variant: This variant (4, also known as delta8+9) lacks two consecutive coding exons, as compared to variant 1. The reading frame is not affected and the resulting isoform (4) lacks an internal segment, as compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G120679 人 GSR (NM_001195104) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 GSR (NM_000637) cDNA克隆 transcript variant 1
人 GSR (NM_001195102) cDNA克隆 transcript variant 2
人 GSR (NM_001195103) cDNA克隆 transcript variant 3
人 GSR (NM_001195104) cDNA克隆 transcript variant 4

基因简介

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2010]

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