人 ADAM18 (NM_001190956) cDNA克隆

Accession: NM_001190956
基因名称: ADAM18
基因别名: ADAM27; tMDCIII
基因描述: Homo sapiens ADAM metallopeptidase domain 18 (ADAM18), transcript variant 2, mRNA.
种属: Human
CDS区长度: 549 (查看编码区序列)
翻译后氨基酸长度: 182 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks multiple 3' exons but has an alternate 3' sequence, as compared to variant 1. The resulting protein (isoform 2) is not disintegrin and metalloproteinase domain-containing protein 18, but represents an uncharacterized protein product.
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G120613 人 ADAM18 (NM_001190956) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a sperm surface protein. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]