人 M6PR (NM_001207024) cDNA克隆

Accession: NM_001207024
基因名称: M6PR
基因别名: SMPR; MPR46; CD-MPR; MPR 46; MPR-46
基因描述: Homo sapiens mannose-6-phosphate receptor (cation dependent) (M6PR), transcript variant 2, mRNA.
种属: Human
CDS区长度: 576 (查看编码区序列)
翻译后氨基酸长度: 191 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks two consecutive exons in the 3' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
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G120535 人 M6PR (NM_001207024) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, May 2011]