人 A1CF (NM_014576) cDNA克隆

基本信息

Accession: NM_014576
基因名称: A1CF
基因别名: ACF; ASP; ACF64; ACF65; APOBEC1CF; RP11-564C4.2
基因描述: Homo sapiens APOBEC1 complementation factor (A1CF), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1761 (查看编码区序列)
翻译后氨基酸长度: 586 (查看氨基酸序列)
Transcript Variant: This dominant variant (1), also referred to as the wild type, differs in the 5' UTR and coding sequence and lacks an alternate in-frame segment compared to variant 5. The resulting isoform (1) has a shorter and distinct N-terminus and lacks a short internal segment compared to isoform 4. Variants 1 and 4 both encode the same isoform (1).

订购信息

产品编号 产品名称 载体 规格 价格
G120325 人 A1CF (NM_014576) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 A1CF (NM_014576) cDNA克隆 transcript variant 1
人 A1CF (NM_138932) cDNA克隆 transcript variant 2
人 A1CF (NM_138933) cDNA克隆 transcript variant 3
人 A1CF (NM_001198818) cDNA克隆 transcript variant 4
人 A1CF (NM_001198819) cDNA克隆 transcript variant 5
人 A1CF (NM_001198820) cDNA克隆 transcript variant 6

基因简介

Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

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