人 IL18R1 (NM_001282399) cDNA克隆

基本信息

Accession: NM_001282399
基因名称: IL18R1
基因别名: CD218a; IL18RA; IL1RRP; CDw218a; IL-1Rrp
基因描述: Homo sapiens interleukin 18 receptor 1 (IL18R1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1158 (查看编码区序列)
翻译后氨基酸长度: 385 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an exon in the 5' region but has an additional exon in a downstream region, compared to variant 1. The resulting isoform (2) has a shorter N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G119837 人 IL18R1 (NM_001282399) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 IL18R1 (NM_003855) cDNA克隆 transcript variant 1
人 IL18R1 (NM_001282399) cDNA克隆 transcript variant 2

基因简介

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

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