人 XCR1 (NM_001024644) cDNA克隆

Accession: NM_001024644
基因名称: XCR1
基因别名: GPR5; CCXCR1
基因描述: Homo sapiens chemokine (C motif) receptor 1 (XCR1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1002 (查看编码区序列)
翻译后氨基酸长度: 333 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an exon in the 5' UTR, as compared to variant 1. Variants 1 and 2 encode the same protein.
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G119762 人 XCR1 (NM_001024644) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]