人 RNF170 (NM_001160224) cDNA克隆

基本信息

Accession: NM_001160224
基因名称: RNF170
基因别名: SNAX1
基因描述: Homo sapiens ring finger protein 170 (RNF170), transcript variant 3, mRNA.
种属: Human
CDS区长度: 603 (查看编码区序列)
翻译后氨基酸长度: 200 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' and 3' UTRs and has multiple coding region differences compared to variant 1. This results in a shorter isoform (b) with a distinct C-terminus, compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G119738 人 RNF170 (NM_001160224) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RNF170 (NM_001160223) cDNA克隆 transcript variant 1
人 RNF170 (NM_030954) cDNA克隆 transcript variant 2
人 RNF170 (NM_001160224) cDNA克隆 transcript variant 3
人 RNF170 (NM_001160225) cDNA克隆 transcript variant 4

基因简介

This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]

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