人 IL25 (NM_172314) cDNA克隆

Accession: NM_172314
基因名称: IL25
基因别名: IL17E
基因描述: Homo sapiens interleukin 25 (IL25), transcript variant 2, mRNA.
种属: Human
CDS区长度: 486 (查看编码区序列)
翻译后氨基酸长度: 161 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses an alternate start codon, compared to variant 1. The resulting isoform (2) has a distinct N-terminus and is shorter than isoform 1.
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G119679 人 IL25 (NM_172314) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]