人 PAEP (NM_002571) cDNA克隆

Accession: NM_002571
基因名称: PAEP
基因别名: GD; GdA; GdF; GdS; PEP; PAEG; PP14
基因描述: Homo sapiens progestagen-associated endometrial protein (PAEP), transcript variant 2, mRNA.
种属: Human
CDS区长度: 543 (查看编码区序列)
翻译后氨基酸长度: 180 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate, in-frame splice site in the 3' UTR, compared to variant 1. It encodes the same protein as variant 1.
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G119587 人 PAEP (NM_002571) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. A number of alternatively spliced transcript variants have been observed at this locus, but the full-length nature of only two, each encoding the same protein, has been determined. [provided by RefSeq, Jul 2008]