人 MTHFR (NM_005957) cDNA克隆

基本信息

Accession: NM_005957
基因名称: MTHFR
基因描述: Homo sapiens methylenetetrahydrofolate reductase (NAD(P)H) (MTHFR), mRNA.
种属: Human
CDS区长度: 1971 (查看编码区序列)
翻译后氨基酸长度: 656 (查看氨基酸序列)

订购信息

产品编号 产品名称 载体 规格 价格
G119573 人 MTHFR (NM_005957) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

基因简介

The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009]

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