人 PTPRO (NM_030670) cDNA克隆

基本信息

Accession: NM_030670
基因名称: PTPRO
基因别名: NPHS6; PTPU2; GLEPP1; PTP-OC; PTP-U2; PTPROT; R-PTP-O
基因描述: Homo sapiens protein tyrosine phosphatase, receptor type, O (PTPRO), transcript variant 6, mRNA.
种属: Human
CDS区长度: 1134 (查看编码区序列)
翻译后氨基酸长度: 377 (查看氨基酸序列)
Transcript Variant: This variant (6) differs in the 5' UTR and 3' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. Variants 4 and 6 encode the same isoform (d), which is shorter than isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G119039 人 PTPRO (NM_030670) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PTPRO (NM_030667) cDNA克隆 transcript variant 1
人 PTPRO (NM_002848) cDNA克隆 transcript variant 2
人 PTPRO (NM_030669) cDNA克隆 transcript variant 3
人 PTPRO (NM_030668) cDNA克隆 transcript variant 4
人 PTPRO (NM_030671) cDNA克隆 transcript variant 5
人 PTPRO (NM_030670) cDNA克隆 transcript variant 6

基因简介

This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer. [provided by RefSeq, May 2011]

相关产品