人 UBXN8 (NM_001282199) cDNA克隆

基本信息

Accession: NM_001282199
基因名称: UBXN8
基因别名: REP8; UBXD6; D8S2298E
基因描述: Homo sapiens UBX domain protein 8 (UBXN8), transcript variant 3, mRNA.
种属: Human
CDS区长度: 690 (查看编码区序列)
翻译后氨基酸长度: 229 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an in-frame exon in the CDS, compared to variant 1. The resulting isoform (3) lacks an internal segment, compared to isoform 1. Isoform 3 is a transmembrane protein.

订购信息

产品编号 产品名称 载体 规格 价格
G118937 人 UBXN8 (NM_001282199) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 UBXN8 (NM_005671) cDNA克隆 transcript variant 1
人 UBXN8 (NM_001282189) cDNA克隆 transcript variant 2
人 UBXN8 (NM_001282199) cDNA克隆 transcript variant 3

基因简介

p97 or VCP (valosin-containing protein) is a versatile ATPase complex, and many cofactors are required for the p97 functional diversity. This gene encodes one of the p97 cofactors. This cofactor is a transmembrane protein and localized in the endoplasmic reticulum (ER) membrane. It tethers p97 to the ER membrane via its UBX domain. The association of this cofactor with p97 facilitates efficient ER-associated degradation of misfolded proteins. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2013]

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