人 OLR1 (NM_001172633) cDNA克隆

基本信息

Accession: NM_001172633
基因名称: OLR1
基因别名: LOX1; LOXIN; SLOX1; CLEC8A; SCARE1
基因描述: Homo sapiens oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 570 (查看编码区序列)
翻译后氨基酸长度: 189 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an exon in the coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G118904 人 OLR1 (NM_001172633) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 OLR1 (NM_002543) cDNA克隆 transcript variant 1
人 OLR1 (NM_001172632) cDNA克隆 transcript variant 2
人 OLR1 (NM_001172633) cDNA克隆 transcript variant 3

基因简介

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]

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