人 JAM2 (NM_001270408) cDNA克隆

Accession: NM_001270408
基因名称: JAM2
基因别名: JAMB; CD322; JAM-B; VEJAM; PRO245; VE-JAM; C21orf43
基因描述: Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 939 (查看编码区序列)
翻译后氨基酸长度: 312 (查看氨基酸序列)
Transcript Variant: This variant (3) contains an alternate 3' terminal exon compared to variant 1, which results in a frame-shift, and a longer isoform (3) with a distinct C-terminus compared to isoform 1.
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G118888 人 JAM2 (NM_001270408) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012]