人 IL37 (NM_173202) cDNA克隆

Accession: NM_173202
基因名称: IL37
基因别名: FIL1; FIL1Z; IL-1H; IL-37; IL1F7; IL1H4; IL-1F7; IL-1H4; IL1RP1; IL-1RP1; FIL1(ZETA)
基因描述: Homo sapiens interleukin 37 (IL37), transcript variant 2, mRNA.
种属: Human
CDS区长度: 594 (查看编码区序列)
翻译后氨基酸长度: 197 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an in-frame coding exon, compared to variant 1, resulting an isoform (2) that lacks an internal region, as compared to isoform 1.
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G118721 人 IL37 (NM_173202) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]