人 VIMP (NM_203472) cDNA克隆

基本信息

Accession: NM_203472
基因名称: VIMP
基因别名: SELS; ADO15; SBBI8; SEPS1; AD-015
基因描述: Homo sapiens VCP-interacting membrane protein (VIMP), transcript variant 1, mRNA.
种属: Human
CDS区长度: 564 (查看编码区序列)
翻译后氨基酸长度: 187 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript. It lacks a portion of the 3' UTR structure and therefore excises the Sec Insertion Sequence necessary for recoding of selenocysteines. This results in a protein (isoform 1) which uses an earlier stop codon and contains a shorter C-terminus, compared to isoform 2.

订购信息

产品编号 产品名称 载体 规格 价格
G118247 人 VIMP (NM_203472) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 VIMP (NM_203472) cDNA克隆 transcript variant 1
人 VIMP (NM_018445) cDNA克隆 transcript variant 2

基因简介

This gene encodes a member of the selenoprotein family, characterized by a selenocysteine (Sec) residue at the active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]

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