人 VEGFB (NM_001243733) cDNA克隆

基本信息

Accession: NM_001243733
基因名称: VEGFB
基因别名: VRF; VEGFL
基因描述: Homo sapiens vascular endothelial growth factor B (VEGFB), transcript variant VEGFB-167, mRNA.
种属: Human
CDS区长度: 567 (查看编码区序列)
翻译后氨基酸长度: 188 (查看氨基酸序列)
Transcript Variant: This variant (VEGFB-167) lacks a segment in the 3' coding region, resulting in a downstream stop codon, compared to variant VEGFB-186. The resulting isoform (VEGFB-167, also known as VRF167) has a shorter and distinct C-terminus, compared to isoform VEGFB-186. This isoform contains the heparin binding domain and is mostly sequestered in the extracellular matrix.

订购信息

产品编号 产品名称 载体 规格 价格
G118207 人 VEGFB (NM_001243733) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 VEGFB (NM_001243733) cDNA克隆 transcript variant VEGFB-167
人 VEGFB (NM_003377) cDNA克隆 transcript variant VEGFB-186

基因简介

This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011]

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