人 FLNA (NM_001456) cDNA克隆

基本信息

Accession: NM_001456
基因名称: FLNA
基因别名: FLN; FMD; MNS; OPD; ABPX; CSBS; CVD1; FLN1; NHBP; OPD1; OPD2; XLVD; XMVD; FLN-A; ABP-280
基因描述: Homo sapiens filamin A, alpha (FLNA), transcript variant 1, mRNA.
种属: Human
CDS区长度: 7920 (查看编码区序列)
翻译后氨基酸长度: 2639 (查看氨基酸序列)
Transcript Variant: This variant (1) is the predominant transcript and encodes a slightly shorter protein isoform (1).

订购信息

产品编号 产品名称 载体 规格 价格
G118129 人 FLNA (NM_001456) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 FLNA (NM_001456) cDNA克隆 transcript variant 1
人 FLNA (NM_001110556) cDNA克隆 transcript variant 2

基因简介

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]

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