人 TGIF2 (NM_021809) cDNA克隆

Accession: NM_021809
基因名称: TGIF2
基因描述: Homo sapiens TGFB-induced factor homeobox 2 (TGIF2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 714 (查看编码区序列)
翻译后氨基酸长度: 237 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All variants (1-4) encode the same protein.
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G117723 人 TGIF2 (NM_021809) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene. [provided by RefSeq, Dec 2010]