人 PPP1R14A (NM_001243947) cDNA克隆

Accession: NM_001243947
基因名称: PPP1R14A
基因别名: CPI17; CPI-17; PPP1INL
基因描述: Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 14A (PPP1R14A), transcript variant 2, mRNA.
种属: Human
CDS区长度: 363 (查看编码区序列)
翻译后氨基酸长度: 120 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an in-frame coding exon compared to variant 1. This results in a shorter isoform (2, also known as CPI-17beta) missing an internal protein segment compared to isoform 1.
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G117584 人 PPP1R14A (NM_001243947) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Sep 2011]