人 FPGS (NM_004957) cDNA克隆

基本信息

Accession: NM_004957
基因名称: FPGS
基因描述: Homo sapiens folylpolyglutamate synthase (FPGS), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1764 (查看编码区序列)
翻译后氨基酸长度: 587 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes isoform (a). This variant has two alternative translational start codons in the same reading frame which encode either a longer, signal-containing mitochondrial protein or a shorter, signal-less cytosolic protein.

订购信息

产品编号 产品名称 载体 规格 价格
G117440 人 FPGS (NM_004957) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 FPGS (NM_004957) cDNA克隆 transcript variant 1
人 FPGS (NM_001018078) cDNA克隆 transcript variant 2

基因简介

This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms. [provided by RefSeq, Jul 2008]

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