人 PLCD1 (NM_006225) cDNA克隆

基本信息

Accession: NM_006225
基因名称: PLCD1
基因别名: NDNC3; PLC-III
基因描述: Homo sapiens phospholipase C, delta 1 (PLCD1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2271 (查看编码区序列)
翻译后氨基酸长度: 756 (查看氨基酸序列)
Transcript Variant: This variant (2) contains an alternate 5' terminal exon compared to transcript variant 1, and initiates translation from an in-frame upstream AUG, resulting in a shorter isoform (2) with a different N-terminus compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G117071 人 PLCD1 (NM_006225) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PLCD1 (NM_001130964) cDNA克隆 transcript variant 1
人 PLCD1 (NM_006225) cDNA克隆 transcript variant 2

基因简介

This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

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