人 FBXL19 (NM_001282351) cDNA克隆

Accession: NM_001282351
基因名称: FBXL19
基因别名: Fbl19; JHDM1C
基因描述: Homo sapiens F-box and leucine-rich repeat protein 19 (FBXL19), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1149 (查看编码区序列)
翻译后氨基酸长度: 382 (查看氨基酸序列)
Transcript Variant: This variant (3) represents use of an alternate promoter and thus differs in the 5' UTR and 5' coding region compared to variant 1. These differences cause translation initiation at a downstream AUG, and the resulting isoform (3) has a shorter N-terminus compared to isoform 1.
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G116918 人 FBXL19 (NM_001282351) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]